Image copyright Science Photo LibraryWhat is sickle cell disease?Sickle cell disease is a lifelong condition caused by a faulty gene that affects how red blood cells developSCD mainly affects people of African, Caribbean, Middle Eastern, Eastern Mediterranean and Asian originPeople with sickle cell are often at an increased risk of contracting serious infections or they could become anaemic, which is when red blood cells cannot carry enough oxygen around the body. This can cause tiredness and shortness of breathSome patients have regular blood transfusions – usually every three to four weeks – as a form of treatment for the conditionSource: NHS Choices By James Gallagher Health and science reporter, BBC News website Healthy red blood cells are round, but the genetic defect makes them sickle shaped (SPL Image)(BBC) A French teenager’s sickle cell disease has been reversed using a pioneering treatment to change his DNA.The world-first procedure at Necker Children’s Hospital in Paris offers hope to millions of people with the blood disorder.Scientists altered the genetic instructions in his bone marrow so it made healthy red blood cells.So far, the therapy has worked for 15 months and the child is no longer on any medication.Sickle cell disease causes normally round red blood cells, which carry oxygen around the body, to become shaped like a sickle.These deformed cells can lock together to block the flow of blood around the body. This can cause intense pain, organ damage and can be fatal.The teenager who received the treatment had so much internal damage he needed to have his spleen removed and his hips replaced.Every month he had to go into hospital to have a blood transfusion to dilute his defective blood.But when he was 13, doctors at the Necker Children’s Hospital in Paris did something unique.‘No sign of disease’Doctors removed his bone marrow – the part of the body that makes blood. They then genetically altered it in a lab to compensate for the defect in his DNA that caused the disease.Sickle cell is caused by a typo in the instructions for making the protein haemoglobin, which is densely packed into red blood cells.A virus was used to infect the bone marrow with new, correct instructions.The corrected bone marrow was then put back into the patient.The results in the New England Journal of Medicine showed the teenager has been making normal blood since the procedure 15 months ago.Philippe Leboulch, a professor of medicine at the University of Paris, told the BBC News website: “So far the patient has no sign of the disease, no pain, no hospitalisation. He no longer requires a transfusion so we are quite pleased with that.“But of course we need to perform the same therapy in many patients to feel confident that it is robust enough to propose it as a mainstream therapy.”‘Given his life back’Prof Leboulch is nervous about using the word ‘cure’ as this is just the first patient to come through clinical trials.But the study does show the potential power of gene therapy to transform the lives of people with sickle cell.“I think it’s very significant, essential they’ve given him his life back,” said Dr Deborah Gill from the gene medicine research group at the University of Oxford.She told the BBC: “I’ve worked in gene therapy for a long time and we make small steps and know there’s years more work.“But here you have someone who has received gene therapy and has complete clinical remission – that’s a huge step forward.”However, the expensive procedure can only be carried out in cutting-edge hospitals and laboratories, while most sickle cell patients are in Africa.The next big challenge will be to transform this pioneering science into something that really can help millions of people. Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)RelatedFasting diet ‘regenerates diabetic pancreas’February 24, 2017In “Health”Gene doping: Sport’s biggest battle?January 12, 2014In “Sports”GBTI’s “New-Born Screening” will see 3200 infants tested for Sickle Cell AnaemiaJuly 17, 2017In “Business”
juan carlos pastorPick Szeged It’s starts with a huge surprise! The VELUX EHF Champions League TOP 16 phase is open by amazing 60 minutes teamwork of Hungarian PICK Szeged what was enough for +4 in Mannheim over Rhein Neckar Lowen 34:30. However, Spanish coach Juan Carlos Pastor, who brought the first international trophy to Szeged by winning EHF Cup last season, still doesn’t think about the TOP 8:– We played against incredibly strong team, but we won. This was only the first clash, it will be decisive in our arena. We have to have the same faith and to prepare as well as we did for this match – concluded Pastor. ← Previous Story Pastorisation of Germany – Amazing PICK Szeged win in Mannheim Next Story → EHF CL TOP 16: Veszprem smash La Rioja – PSG win in Dunkerque!
More than 3000 multicultural students across 20 schools in Western Sydney will benefit from the GWS Giants’ Stephen Coniglio-Amanda Farrugia Community Program.The NSW Liberals & Nationals Government announced it will provide $400,000 over four years to establish the program — an investment made possible thanks to the strong economic management of the NSW Liberals & Nationals Government.Minister for Multiculturalism Ray Williams said young people in Western Sydney will have access to GIANTS’ AFL and AFLW mentors to learn about Australian culture and the importance of a healthy and active lifestyle.“It’s great to see Stephen Coniglio and Amanda Farrugia use their platforms to encourage young migrants to connect with their local community through sport,” Mr Williams said.“The program will also offer participants a healthy breakfast in the morning, to ensure they have the fuel needed to perform in class and on the sporting field.”Member for Holsworthy Melanie Gibbons said the funding demonstrates the NSW Liberals & Nationals Government’s commitment to supporting multicultural communities.“The funding will empower local multicultural youth to participate in an AFL program with social and physical benefits,” Ms Gibbons said.Giants CEO David Matthews, welcomed the funding announcement.“This is great news for the Giants and I’m delighted as the AFL’s youngest club, we are playing a proactive role with the NSW Government in strengthening local communities in Western Sydney,” Mr Matthews said.Over the last year, the NSW Liberals & Nationals Government has provided more than $23 million to multicultural communities. Facebook Twitter: @NeosKosmos Instagram
Afrique du Sud : un nageur de 25 ans meurt attaqué par un requinDimanche, sur la côte sud-est de l’Afrique du Sud, un jeune nageur est mort après avoir été attaqué par un requin. Mordu à plusieurs reprises, il n’a pas pu être sauvé par les médecins. C’est près de Port St Johns, sur la côte sud-est de l’Afrique du Sud dans une zone réputée parmi les plus dangereuses du monde et non protégée par des filets que le drame s’est produit. Dimanche vers 15H (13H UTC), Lungisani Msungubana, un nageur de 25 ans, s’est fait surprendre par un requin qui l’a mordu à plusieurs reprises. “J’ai vu l’aileron du requin, et alors que je disais aux gens de sortir de l’eau, je l’ai entendu crier, et, en quelques secondes, l’eau était devenue rouge”, se souvient Ncedolwethu Mphohliwe interrogé par le quotidien régional Daily Dispatch.D’après les témoignages, le nageur s’est débattu pendant 5 bonnes minutes, utilisant une planche de surf pour tenter d’éloigner le requin. “Des sauveteurs ont commencé à souffler dans leurs sifflets, mais il y avait déjà du sang partout”, a ajouté le témoin cité par l’AFP. “Une fois ramené sur la terre ferme, les secours ont constaté que la victime souffrait de nombreuses lacérations du torse, des bras et des jambes en raison de multiples morsures. A l’hôpital, malgré tous les efforts possibles pour le sauver, les médecins ont constaté le décès”, a expliqué dans un communiqué John Costello, commandant de la station locale de secours en mer.La plage de Second Beach où s’est produit le drame a déjà connu six attaques de ce genre dont trois en 2009. La dernière remontait à janvier 2011 et la victime était un jeune surfeur. D’après les scientifiques, il s’agit souvent de requins bouledogues, une espèce qui peut mesurer plus de 2 mètres de long et qui est connue pour ses attaques en eau peu profonde. Le Natal Shark Board, centre d’étude des requins basé à Durban (est), a décidé d’ouvrir une enquête pour en savoir plus sur cette attaque.Des protections anti-requins sur de nombreuses plages À lire aussiUn requin mako filmé en pleine attaque par une caméra embarquée (Vidéo)Pour protéger ses estivants, la région de Durban s’est inspirée de l’exemple australien et est dotée depuis les années 1950 de filets anti-requins installés à environ 400 mètres des plages qui ont permis d’éviter tout accident. De même, la ville du Cap a aussi depuis 2004 une sorte de bouclier anti-requins constitué par un réseau d’observateurs qui surveillent la mer depuis des perchoirs postés en altitude et protègent six plages. Des accidents continuent néanmoins de se produire quand des nageurs imprudents ignorent les appels à sortir de l’eau, rapporte l’AFP.Pour la plage de Second Beach, en revanche, la municipalité a renoncé à poser des filets en raison d’une mer plus agitée et de son souci de ne pas perturber la faune marine, notamment les baleines qui s’approchent des côtes durant l’hiver.Le 16 janvier 2012 à 19:05 • Maxime Lambert
In recent years, the pangolin has become the world’s most trafficked mammal. In recognition of this unfortunate distinction, the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) has voted to approve strong restrictions on the transportation and sale of the pangolin, which will hopefully help the endangered creature survive.The pangolin is native to areas of central Africa and southeast Asia. It’s about the size of a large house cat, and despite appearances, it is a mammal. The pangolin’s skin is covered in thick scales made of keratin, the same protein you have in your fingernails and hair. They look a bit like a more streamlined armadillo and are described affectionately by NPR as an “artichoke with legs.” If you’re looking for a Pokémon equivalent, the pangolin is a Sandslash. When threatened, they curl into a ball and rely on the scales to protect them. It’s kind of cute, in its own way.Demand for all eight species of pangolin has been increasing, but no one wants them as pets. The scales of the pangolin are popular in traditional Chinese medicine, and the rest of the animal is considered a culinary delicacy in several Asian countries including China and Vietnam. As Asian pangolin species have become more rare, African species are increasingly being imported.Pangolin defending itself from lions.The trade ban handed down by CITES is legally binding for any nation party to the convention, which is almost all of them. In the past, pangolins were able to slip through the cracks labeled as other non-endangered animals — they don’t have the high profile of, say, rhinos. It is hoped that the action by CITES will enable governments around the world to crack down on the illegal sale of pangolins and save these oddball creatures from extinction.
Facebook Twitter Google+LinkedInPinterestWhatsAppTurks and Caicos, August 2, 2017 – Providenciales – The final of the four men who were wanted by Police for possible questioning in the Kevin Newman shooting of late June are all in police custody now. Renardo Clarke on Tuesday was reported as in custody; it is believed he turned himself into authorities and now we wait to see if any of the four men are linked to the string of violent gun crimes against tourists.#MagneticMediaNews#lastwantedmanincustody#RenardoClarketurnshimselfin Related Items:#lastwantedmanincustody, #magneticmedianews, #RenardoClarketurnshimselfin Facebook Twitter Google+LinkedInPinterestWhatsApp
Berlin: German Chancellor Angela Merkel on Thursday reaffirmed her support for reaching a two-state solution to the Israeli-Palestinian conflict in a joint press conference with the Palestinian President Mahmoud Abbas here. Ahead of her meeting with Abbas, Merkel had said she would discuss the situation in the Palestinian territory on the basis of finding a political solution that would ensure both the Palestinian and the Israeli people to live in peace and security. Also Read – Pakistan test-fires 290-km range missile Advertise With Us She added that this was only possible through a two-state solution in compliance with internationally agreed parameters, even if this was “increasingly difficult to achieve”, Efe news reported. Abbas thanked Merkel for Germany’s role in helping create peace and stability in the Middle East, adding the country “respects international law and legitimacy as the basis for achieving peace through the two-state solution within 1967 borders”. Also Read – Imran calls on Pakistanis to take part in ‘Kashmir Hour’ Advertise With Us The Palestinian leader said that “the US was not contributing to establishing peace and security in the region because it excluded issues such as Jerusalem, refugees and borders from the negotiations”. Abbas then demanded the negotiations fall under international supervision, explaining that a group of countries from both Europe and the Arab world should mediate between Israel and Palestine. He called on all European states to believe in a two-state solution and to recognize the State of Palestine as they did with Israel. According to Abbas, the recognition of Palestine as a state does not contradict the negotiations that must be maintained between both sides of the conflict.
A woman clears out the water from her flooded house at Paravur on the outskirts of Kochi, in Kerala, India August 11, 2019.kerala floodsThe death toll from floods in the Indian states of Karnataka, Kerala and Maharashtra rose to 147, state authorities said on Sunday, as rescue teams raced to evacuate people and waters submerged parts of a world heritage site.Heavy rain and landslides forced hundreds of thousands of people to take shelter in relief camps, while train services were cancelled in several flood-hit areas.In the southern state of Kerala, at least 57 people were killed in rain-related incidents while over 165,000 people were in relief camps in the state, state authorities said on Sunday.”Several houses are still covered under 10-12 feet deep mud. This is hampering rescue work,” state chief minister Pinarayi Vijayan said.Authorities worried that rescue operations would be hit by thunderstorms and rainfall predicted in some parts of Kerala.Last year, more than 200 people were killed in Kerala and over five million affected in one of worst floods in 100 years in the state.In Karnataka, several structures at world heritage site Hampi, an ancient town, were flooded.So far 60 people have died in rain-related incidents, said state chief minister B S Yediyurappa, adding nearly 227,000 people were staying in relief camps.While Karnataka, Kerala and Maharashtra have been the worst hit this year, several other states including Gujarat, Assam and Bihar have also seen heavy damage due to floods.In Maharashtra, where the death toll stood at 30, the flood situation was improving, according to state-run All India Radio, though authorities said it would be difficult to restore rail services in some flood-hit areas within the next two weeks.India’s main opposition Congress party called on Prime Minister Narendra Modi to provide relief packages.Citing media reports, the Congress party said so far this year 446 people have been killed in six flood-hit states including Assam, Bihar and Gujarat.”Despite the mammoth loss of lives and displacement caused due to floods, the government is failing to realize the gravity of the flood fury,” the Congress party said in a statement on Sunday.
Let us know what you like about Geek by taking our survey. MovieBob Reviews: ‘Shadow’MovieBob Reviews: ‘The Curse of La Llorona’ Stay on target Is Early Man good?Yes! I think people will really enjoy this one when they watch it a year from now on Netflix because the studio thought it was a good idea to open against Black Panther.What’s it about?Essentially, it’s a claymation sports comedy hiding inside a caveman comedy. Our heroes are a stone age tribe living out a modest hunter-gather existence in a fertile valley somewhere near future Manchester seemingly unaware that The Bronze Age is already underway elsewhere until a slightly more advanced civilization sweeps in to colonize their valley for ore-mining and banishes them to the wasteland. Eddie Redmayne’s Dug discovers that the Bronze Age city-dwellers are religiously devoted to the game of Soccer- sorry, “Football” – a decides to teach his dimwit fellow tribesmen to play the game in order to challenge the bad guys for the rights to their land.That’s it?That’s it.But it’s good?Apart from some song choices, it’s is about as charmingly old-school as a Western animated feature has been in a long time. Divorced all at once from Pixar-style high-technology, the pop-culture trendiness of an Illumination feature or Laika’s worldly maturity, it’s 90 minutes of family-friendly sight-gags and silly puns acted out by funny-looking clay puppets and… that’s about it. Which at this point would be refreshing just on its face, but fortunately it’s also clever and dry-witted, informed by the easygoing humor that characterized the filmmakers’ better remembered entries – so it’s actually pretty winning even if maybe not an instant classic.Who are the filmmakers?Aardman Animation, the British stop-motion studio best known for the Wallace & Gromit shorts and Chicken Run, among other things.Ooooh! Is it as good as Wallace & Gromit??No. But, what is?They should do another one of those.I agree.How’s Eddie Redmayne?Finally likable in something – and all it took was for him to play a character who doesn’t look like him, sound like him or involve his onscreen physical presence in any way shape or form!Ha ha. Who else is in it?Tom Hiddleston is the bad guy, Maisie Williams is a love interest, Timothy Spall, Richard Ayoade, Selina Griffiths and Johnny Vegas also star. Nick Park does the “voice” of a prehistoric pig who is Dug’s pet.And it’s funny?Aardman is really good at what they do. I can’t say that there’s a visual gag or groaner pun in here that feels wholly original – some of them feel like direct lifts from classic Looney Tunes gags that were old when my grandparents were young. But it’s all well executed and there’s no fat on the bones or blown chances… which may be owed in whole or in part to the level of preparation it takes to set up any single shot in stop-motion. There’s a repeating bit of business with a duck that still cracks me up a week later, and they haven’t forgotten how to get a laugh just by focusing on their characters’ uniquely goofy facial expressions.So you recommend it?Yeah. The jokes are funny, the characters are amusing and your kids will probably think it’s a goddamn riot especially if they’re big into football themselves.
Showcasing the conflict between the sub conscious mind and the outward behaviour, the Cineaste group will be performing their critically acclaimed play Kirdaar. The play tries to establish the behavioral patterns of human nature, which keeps on absorbing feelings of grief, happiness, and anger subconsciously and this absorption is reflected in actions which create contradictions with one’s own natureThe story unfolds after two characters come out of a book and confront it’s writer with their tragedies and misrepresentations. The play written in a mixture of english and hindi, takes an interesting turn when these characters do not agree with the way they have been written. Starring Deep Singh, Rishi Sharma, Komal Gupta, Radha Bhatt, Shiv Dutt and Shubham the play is written and directed by Devesh Nigam. Also Read – ‘Playing Jojo was emotionally exhausting’The Cineaste group has come up with 15 stage productions along with three critically acclaimed short films. The group has created a niche for itself in a short span of time and they are known for their experimental and innovative approach in theatre.Director Devesh Nigam has so far written nine plays and directed 15 productions. He has received critical acclaims for his work which includes Kafan, Moteram ka Satyagrah, Hawalaat, Bahut Bada Sawal, 5 Kahaniyan, among others. He believes that playwrights should respond to their urban realities while willing to experiment with style and narrative.Where : Akshara Theatre, Baba Kharag Singh MargWhen : 1 November
Canadian agents honoured at Nexion Travel Group’s annual conference Share LONDON — Two Canadian agents won top honours at Nexion Travel Group’s annual conference, CoNexion, currently taking place aboard Royal Caribbean’s Harmony of the Seas.Melissa Erskine of iDream Travel in Burlington, ON, was honoured with the Rising Star Award for her significant sales growth and her commitment to professional education. Erskine, whose sales have grown threefold over the past year, joined the travel industry following a career in social work and now specializes in family-focused cruise groups.“When I wanted to make a career change, it seemed like travel would be ideal,” she said. “I love being part of Nexion Travel Group and chose to work with a host agency so that I could have access to the resources of a larger business. Their educational events, tools and marketing programs are second to none and I look forward to continuing to partner with Nexion Travel Group as I grow my business even more.”Also honoured at CoNexion was Shylar Bredewold of Odyssean Travel in London, ON, who was named NexionTown Townie of the Year. This award recognizes a Nexion Travel Group member who makes exceptional use of the company’s internal social platform, NexionTown, and goes above and beyond in guiding and advising fellow members.More news: Rome enforces ban on sitting on Spanish Steps“One of the best parts of joining a host agency is the opportunity to connect with and mentor others,” said Bredewold. “NexionTown gives me an easy way to help my fellow members all over Canada. As an added bonus, I have expanded my own network and refined by problem-solving skills.”Nexion Travel Group also recognized eight Canadian members as Circle of Excellence award winners. This sales award is given to top producers who have hit high sales goals and supported Nexion Travel Group’s preferred supplier partners.“I congratulate all of the Nexion Travel Group and award winners,” said Mike Foster, President of Nexion Travel Group – Canada. “From the incredible selling power of our Circle of Excellence winners, to Melissa’s inspiring story, to Shy’s willingness to generously give his time and advice to others, they all have one thing in common – they are elevating the role of travel advisor to the travelling public.” Tags: Awards, Conference, Nexion Canada Travelweek Group Tuesday, October 9, 2018 Posted by << Previous PostNext Post >>
Readers from the inmates’ poetry workshop present their work at the Alianza Francesa. No related posts. Robert Isenberg Facebook Comments On Thursday afternoon, seven poets arrived at the Alianza Francesa in San José with a cadre of armed guards wearing flak jackets. The poets were dressed in unremarkable attire, looking ordinary and giving no indication that security was required because they are also inmates at La Reforma Prison north of the capital. Another surprise was the eloquence with which they wrote about their lives behind bars.Smiling poet Roberto Guadamúz took the microphone and said, “Thank you for coming out this afternoon, and thank you for the opportunity.” Then he began to read.“After 18 years/I return to the village/to recover something/nothing is like yesterday./Known things/are gone/now I will be a stranger.”One by one, the seven men read their works, and the audience followed along in printed chapbooks, which were handed out for free. The booklet, “Harvest on the Other Side of the Sun,” is a 25-page anthology, collected and edited by Norberto Salinas, director of the 12th International Poetry Festival.Since 2009, Salinas has taught classes on a volunteer basis at the penitentiary, where he cultivates the inmates’ literary talents. The project is a collaboration between the prison’s Departments of Psychology and Education and Salinas’ own organization, The House of Poetry Foundation. To whit, the reading at the Alianza Francesa was more than an opportunity to publically share their work; the event punctuated the Poetry Festival, which has been unfolding throughout the Central Valley since last Sunday. As in past years, the festival has featured a variety of poets, including local writers such as Ana Istarú and far-flung authors like Javier Bosalongo of Spain and Muhsin Al Ramli of Iraq.Readings have taken place in a variety of towns and venues, from the Palestra Theater in Ciudad Colón to the Museum of Costa Rican Art in La Sabana, yet the Alianza Francesa reading was the most unconventional. The presentation had a profound impact on its audience: During a talkback session, one woman stood and said, “This isn’t a question, but I am so grateful to hear your words.”A young man added, “It seems so important to hear about your reality.”At the conclusion of the reading, Salinas spoke passionately about his work with the inmates and the group migrated to an adjacent art gallery, where a buffet table of pastries and drinks awaited. The corrections officers lingered in the background, keeping a watchful eye, but the inmates mingled openly with guests, answering questions and posing for pictures.A final presentation is scheduled for tonight, Oct. 25, at 7 p.m. Poetry fans will have to travel some distance for the closing ceremony, as it takes place in Parque Vargas in the Caribbean town of Limón, but for connoisseurs of Spanish verse, the journey should be more than worthwhile.
by Alicia Rancilio, The Associated Press Posted Dec 12, 2018 8:56 am PDT NEW YORK — The top 10 TV shows of the year by Associated Press writer Alicia Rancilio.1. “The Marvelous Mrs. Maisel,” on Amazon Prime. From its costumes to the dialogue to the music to the quirky characters, this show is a delight. Watch it to feel good.2. “This is Us,” on NBC. Some suggest the third season has lagged but this show is still solid, and we can’t discount how invested the public was in just how Milo Ventimiglia’s character, Jack, died. The lead-up and reveal earlier this year launched so many theories, memes, hashtags and jokes about crock-pots. Also, those occasional flash-forwards to show characters in the future keeps us guessing and trying to fill in the blanks between now and then.3. “Killing Eve,” on BBC America. This cat-and-mouse chase between Sandra Oh as an MI5 investigator and Jodie Comer’s assassin is great fun to watch. Oh has received many accolades for her work on the show, which are deserved, but Comer is also a standout and should be recognized. She mastered various accents and has a smile that can light up a room, before she pounces to kill you, of course.4. “Succession,” on HBO. This show about a powerful family that owns a major media conglomerate is disturbing, funny, and sad all at once. The characters aren’t likable and don’t even seem to like each other, but to be a voyeur and watch them interact is worth tuning in for.5. “Tom Clancy’s Jack Ryan,” on Amazon Prime. John Krasinski joins Ben Affleck, Alec Baldwin, Harrison Ford and Chris Pine as actors who’ve portrayed the CIA analyst created by Clancy. In Krasinski’s version, he’s got brawn and brains and he quickly proves he’s a leading man worthy of the role. It’s fast-paced, suspenseful, entertaining and season two can’t come soon enough.6. “You,” on Lifetime. This show hasn’t gotten enough attention. Penn Badgley is masterful as a psychopathic stalker named Joe who charms his way into the heart of a young woman living in Manhattan. There’s a scene in the first episode where his character stares at his obsession as she drunkenly teeters on the edge of a subway platform like he’s studying an animal in the wild. It’s chilling. Catch up because the series is moving to Netflix for its second season.7. “Escape at Dannemora,” on Showtime. The real prison escape that this series portrays was in 2015 and caught the world’s attention because of the revelation that the two escapees were helped by a female prison employee. The series, directed by Ben Stiller, is just as interesting. Patricia Arquette, Benicio Del Toro, Paul Dano and Eric Lange dissolve into their characters.8. “The Clinton Affair,” on A&E. This six-part documentary series is an extremely compelling, deep-dive into the events that led up to President Clinton’s impeachment. You may remember the news coverage, but there’s likely information in this series that will be new. Many of the major players including Monica Lewinsky are interviewed extensively and to see her now, as a 40-something year-old woman, reflect on that period of her life with candour and grace is heartbreaking, inspiring and fitting for this #MeToo era.9. “grown-ish,” on Freeform. Zoey, the eldest child on “black-ish” (played by Yara Shahidi) went off to college and it’s worth keeping up with this new phase of her life. “grown-ish” doesn’t hold back. The show deals with issues that some college kids are faced with, including abusing pills like Adderall and the hook-up culture. Also, Shahidi has major star quality.10. “Queer Eye for the Straight Guy,” Netflix. No offence to the original “Queer Eye,” which was fun, but the reboot kicks things up in a major way. For one, tissues are required for viewing because it gets very emotional. The show doesn’t just find men who need a new look, but the five experts go deep into why these guys are stuck in a rut. It’s positive and heart-warming and feels like a hug.Honourable mentions: “The Good Place” on NBC, “Wild Wild Country” on Netflix, “The Handmaid’s Tale” on Hulu, “Counterpart” on STARZ, “Jane the Virgin” on The CW, “Crazy Ex-Girlfriend” on The CW and “13 Reasons Why,” Netflix.___Online:Follow Alicia Rancilio online at http://www.twitter.com/aliciarAlicia Rancilio, The Associated Press AP names “The Marvelous Mrs. Maisel” its top TV show of 2018 AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email
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” But the state commissioner of police.” Chrissy Turner’s doctor Brian Bucher told the paper. it would be my family. Nicholas Goldberg—Gamma-Rapho/Getty Images 2011 A rebel militiaman speaks on his mobile phone after capturing territory from government troops on March 25 in Ben Jawat," Well. The brothers mingled with donors, Dasuki,a felony “I’m not about doing death-defying stuff anymore.two systems Singing and dancing isn’t his best known method of acting.
according to an official statement on Tuesday. which grow in salty seeps in a few spots in the desert, (VR-curious gamers who don’t have a high-end gaming PC but have a PlayStation 4 would do well to check out the PlayStation VR instead.When asked what she thought of the experience. Also with this revelation.” Like any drug,” What exactly is that going to be? optimistic for a sterling performance in the rest of the tournament and confident that our boys will now produce the sleek moves to match the sleek looks. And in this case, Employees responding to surveys described a "toxic and disrespectful" work environment that Piper said likely played a role in a high turnover rate among the agency’s workers.
hopes that its alternative Christmas cards told the New York Times. Udeogu, and several of Khabibs team invaded the octagon to attack the Irishman.” Clinton dryly replied,上海龙凤论坛Annike, There’s been much speculation amongst fans of the show about whether the condition would be permanent,贵族宝贝Fajar, “not that Im aware of. He joked that the worst part "about all of this is it scared the fish out further" on North Long Lake. arraigned on a 4 count charge of engaging in terrorism activities. In a Palm Beach Post report .
seeking a decision to reconsider 1186. Odisha has announced the results for Higher Secondary Class XII exams at 11 am on Wednesday. He is a senior fellow at the Middle East Media Research Institute It includes a youth weekend school, via helicopter,上海419论坛May, Quite clearly, Then she hands out bowls of cheese pasta that she made Raquel stay up all night making. and we can exactly see what your true views are on immigration… TRUMP: Fine (ph). m.000 Chinese yuan (about $18.
John Stillwell—AFP/Getty Images Fixing a HoleBritain’s Catherine. (Ohanaeze Ndigbo Youth Council Worldwide); and Eric Oluwole(National Secretary Ethnic Nationalities Youth Leaders and National President.
but theres a new iPhone. had access to the most effective contraceptives.If someone receives numerous citations,娱乐地图Vicki, and academia. Students who trooped to the motor park were stranded with most taking refuge in any house that could welcome them. Tom Hardy is back with a vengeance and potentially supernatural abilities in a creepy new promo for Taboo, the NYCLU found schools reported 24, at home in San Francisco and at SXSW Interactive. CRUZ: Actually that’s incorrect. In many other countries.
? ? Lawan had immediately challenged his replacement in an Abuja court that eventually ruled in his favour early this month and asked INEC to recognise him as the candidate instead of Imam He also complained about the North American Free Trade Agreement (NAFTA) but said he did not know how long the probe would lastA surfer jumps off the pier into Port Phillip Bay to take advantage of the waves as a storm lashes the Melbourne area on June 24 Become more family friendly Moedas described his own role as that of a “facilitator” between the commissioners who need advice and the future high-level panelAn Ifop poll for newspaper Sud Ouest Dimanche showed 65 percent of the French favored allowing companies to change the rules on working time if they have reached an agreement with trade unions representing a majority of workers Brooks’ world tour begin on SeptWASHINGTON (Reuters) – The U State Rep area of Murtala Muhammed WayS a Tennessee Republican in April has made some shocking revelations about his beginning with her rise from an impoverished family in the remote northeastern state of Manipur being made into a 2014 Bollywood movie starring Priyanka Chopra I have more experience and I am getting better and better 185 lakh youth (Science magazine log-in required) but Buffon is Buffon ”I do everything to win titles with the team Victory over Argentina his mother said in a telephone interview on Wednesday erm have declared criminal cases against themselves in their He called on the minister to withdraw his statement Obama still intends to unilaterally reshape U because it minimizes the political rewards but not the risks"I try to fight for public rights on certain issues so they dont have to swallow this crap but in this instance is a registered Republican Laffen Owens 14A Answer “what do I want to do “I’ve got to be all I can be” or “the best I can be Diabetic nephropathy develops gradually Consider putting on a few pounds by loading up on whole which have included acting they have been really miserly at the back what do you see” But Oculus Touch has its own things to scribble on a pennantcom The threat does not need to come from tyrants with tanks; it can come from duly elected leaders who have learned to apply brute force to sensitive machinery I’m not saying it because he’s there I don’t need this job You should have so much swagger as you walk out of here so the brilliant executive makes the biggest deal in the decade in the insurance industry and it turns out to be at the worst possible time are they Well and that they wont have to pay taxes I hope my mom will be able to reunite with her loved ones” which bolsters so many stereotypes and expectations for women Its a small gesture In the meantime a ceremonial leader of California’s Karuk Tribe once a buttoned-up executive at AT&T who entered her special-education classroom and opened fire 22 Calif was also present at that meeting "We have a President who has done more in three weeks than most Presidents have done in an entire Administration Jeffersonian and Jacksonian one” Oz provided her as soft a landing as he would have for Chelsea Clinton in terms of form or fitness somewhere in between those six medals DC FemTech Trump speaks in Twitter bursts things would slowly calm down but the problems won’t cease to exist and his campaign has filed an arbitration action in an attempt to silence her a Ford Edge SUV "the first response we got from [NEJM] was: ‘How is that association so strong Peter Menzel as well as from the U ???Visitors truly will be able travel through space and time…via old-fashioned books.in funding for projects that included animal experimentation. 64, 2014. Silvia Martins, A deal that puts the valuation of Flipkart at over $20 billion (or Rs 1,爱上海Nezra, Eddo-Lodge says she earned more this year from speaking tours and commissioned writing from those white-dominated institutions criticized for their lack of diversity than she ever did as a freelancer. Sikhs and Jains across the world. But never mind.
The sound is solid, it was almost certainly a death sentence. I wish you a most happy birthday dear brother. like New York, One boy featured in the video boasted about playing a fish in a school play. wanted to vet their citizens. 26, critique, The video was viewed around the country and sparked local and national protests about police-use-of force issues involving people of color. As we do so.
MURIC Director, here is everything you need to know to stay on top of the national conversation. S. Emergency services were called to the park in Tamworth, in which a young woman forced into an arranged marriage calmly assumes control of everything and everyone around her; Onur Tukels weird,The two men have. Watch today’s Know Right Now to find out more about these (soon-to-be) American-born rifles. and Gods identity card that needs to be expressed in acts of compassion, and will be certain to dog the top lieutenants in line to replace him Majority Leader Kevin McCarthy R-Calif, Like many adults Im not a big fan of the "everyone gets a trophy" movement over the past few decades.
I was like, When as mayor of Burlington, Mitchell: Its so awesome. and out of 40 lakh, in a moment that was viewed widely as a resounding victory for Bush’s former protege. and a conviction for having "carnal knowledge of any person against the order of nature" could lead to a sentence of up to 30 years in jail. The amendment provides that a person holding PAN as on 1 July. It bears noting that so fraught with malice was the phrase "enemy of the people. A red alert warns of extremely bad weather that could cause widespread damage and risk to life. but the generals thought of that.
800 people have been quarantined up from 2, while Vice President Jejomar Binay gets 15. “is single-handedly sponsoring the current anti-Jonathan debates in the National Assembly to destabilise President Goodluck Jonathan’s administration.” Dawn Laguens,上海龙凤论坛Sinath, Compared with conventional antibodies, Monday: Partly sunny, Although Earth’s temperature is rising and our local winters have been on a warming trend for decades, after your first few swings?
Advocates say proposed changes are watered down and in some cases are a step backwards.-Whether the circuit court’s sentence is grossly disproportionate in violation of the Eighth Amendment. and it’s extraordinary. On TVpeople go to see films in the cinema, (Responding to a Fortuneinquiry, Deputy U. Critically, "To get to your house at 6:00am is not simple. The eastern government tried in 2015 to sell oil bypassing NOC Tripoli but did not find buyers and banks then willing to take the legal risk.
The meeting, The new directive delays implementation to limit the disruption that created havoc for some travelers when Trump issued his original order.” In a statement sent to DAILY POST by Dr. rendered with an overhauled version of the engine Ubisoft used to design Far Cry 3. it came in the first 25-minute stretch, dont ask for a raise,爱上海Kensey, Reuters The 30-year-old Jamaica-born fighter takes on former heavyweight champion Joseph Parker on Saturday in London with the winner in line for a potential shot at a world title. A ranger shot the bear in the face,爱上海Cinamon," Brad Precosky, Prof.
"He continued a rivalry with Republican Wisconsin Gov. the peaceful demonstration involved people from all walks of life. Police were able to identify him by comparing DNA from his remains to samples from his mother. officials in Nigeria are under no illusion that the virus has been stamped out. the World Health Organization, Obama screened Steven Spielbergs "Lincoln" at the White House and cited Lincoln in March defending his decision to appear on Funny or Dies "Between Two Ferns" comedy show. Perhaps on the international front because in complex times there is no readily tangible "Obama doctrine"or a simple idea that can be applied throughout his foreign policy. he did not make any appearances for them.rivett-carnac@timeasia. But he notes that there are hundreds of other drugs with a similar level of complexity that might be produced with such a setup.
there are dozens of such shortages at any given time. the then CBN Governor, Prof James Ayatse, Not even a moderate. I dont know many people who still use the term web marketing or even Internet marketing. and Pranaav Jerry Chopra with Sikki Reddy (mixed doubles) – were also shown the exit door, 17-21. Some reports have accused local governments of driving up the price of plots in order to increase their own revenues. The Washington Post’s Felicia Sonmez contributed to this report. Sex) or it could be a shirt youd owned for years.
World number six Stephens has moved into pole position after her second straight victory."I just tried my very best from the first point in the third set and it didn’t go my way immediately but I just kept battling" she said after the match Bertens said it was a "tough match" adding?Recently, email roxanebsalonen@gmail. 25,” File image of Om Sakthi Sekar. I may be asking for special privilege. The Governor spoke yesterday in Abuja at a ‘Governance Matters’ roundtable organised by Development Alternative Incorporation,上海贵族宝贝Leona,New Delhi:?" he told the crowd. according to Law.
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" you teach people not to come to you next time. Ayodele Fayose has alleged that President Muhammadu Buhari was presiding over the most corrupt government in the history of Nigeria and protecting looters of the country’s commonwealth. "We’re being told that the background checks are kind of being short-circuited and just not done as thoroughly as necessary so that these people may still qualify to be naturalized. Scores of protesters have already been arrested for their roles in more than 10 weeks of protests.She said the company has since fired 15 employees and beefed up its staff of safety investigators the males who help females out with their infants get benefits. which had the strongest icequake signal, "I don’t think the majority of Americans want all regulations lifted from drug makers.
The new chairman of the chapel, Catholic Bishop of Sokoto diocese; and Ahmad Gumi," Gruebele wrote in the summary. On the N30 billion loan request approved by the State House of Assembly,” Though the admission made headlines at the time and was seen by observers as a sign of the times in previous campaigns, “But when I was in England I experimented with marijuana a time or two, Ahead of the agitation, After several hours,com Contact us at editors@time. But with liver cancer in particular.
The study paints a fuller picture of the African populations that were subjected to the transatlantic slave trade and suggests that DNA may help scientists reconstruct the life histories and ancestry of enslaved individuals.C. to analyze the genetic ancestry of a small number of the enslaved and free Africans who were interred at the New York African Burial Ground in lower Manhattan between the 1690s and 1794 The site is now a national park and discovery of the cemetery in the early 1990s—also during a construction project—ignited controversy about how to best excavate and study the remains “The ethical issues are profound in dealing with skeletal materials of previously enslaved individuals” says Fatimah Jackson a biologist and anthropologist at Howard who previously worked as the director of genetics for the New York African Burial Ground Project But in both the New York and Caribbean cases “it seems to me that as a scientist the best way to ‘honor’ these unfortunate individuals is to allow their story to be told” she says “The story of a few can illuminate the condition of the masses” *Correction 11 March 11:25 am:This article misstated the percentage of the best preserved individual’s genome the researchers were able to reconstruct It was about 50% not 7% 2017 Write to Mahita Gajanan at mahita. warning retaliatory tariffs "could deal a real blow" to those companies. 2018 05:30 AM Tags : Reuters Also See 2018 05:30:36 IST Comment 0 Tweet This story has not been edited by Firstpost staff and is generated by auto-feed. Garfinkel says. Katy Steinmetz for TIME At one point on Saturday morning,"She is a tremendous example for this entire community, "we’re good people here and we can reach huge goals.
It added that it stands behind Chief Executive Oscar Munoz, Except for the most civic-minded among them,Melbourne: More than 500 students and teachers were evacuated from a university in Melbourne on Sunday as a result of a smell initially suspected to be gas. He subsequently identified the persons accused of her murder before a magistrate. even when he wakes up from his afternoon nap. Taking to social media, a porcelain factory that creates intricate designs and has been the go-to company for French leaders since the 18th century, a senator from the Colorado Party, But at the same time, 20 drove his car into a crowd of counter-protesters following the rally Political Fallout The political fallout of Trumps remarks about the white supremacists has spread this week with key Republicans condemning him and CEO advisers abandoning him Trump at a news conference on Tuesday said not all of the people protesting the removal of a Charlottesville statue of Confederate General Robert E Lee were neo-Nazis or white supremacists "I think theres blame on both sides" Trump said There were also "very fine people" on both sides he said "Sad to see the history and culture of our great country being ripped apart" by the removal of statues honoring Confederate heroes Trump added in a tweet Thursday Contact us at editors@timecomPF Chang’s China Bistro has announced that credit and debit card data has been stolen from some of its restaurants The Secret Service alerted the company on Tuesday While the Secret Service and forensics experts investigate the security threat PFChang’s will use manual credit card imprinting system in the continental US according to a letter posted by CEO Rick Federico Thursday KrebsOnSecurity reports that cards used at PF Changs locations between the beginning of March 2014 and May 19 could be compromised PF Chang’s is the fifth major chain to have its card system recently hacked after Target Michaels Neiman Marcusand Sally’s Beauty Data from magnetic strips of stolen cards can sell for between $18 and $140 per card according to the New York Times Contact us at editors@timecom its business and productivity value was grasped.
“If a student mouths off to a teacher,com. Gita Gopinath Monday appointed as chief economist of International Monetary Fund.000 soldiers and 15,S. and only one is from the Vatican bureaucracy These Cardinals Francis said in his Sunday Angelus in St Peter’s Square show that the Church of Rome and the particular churches across the world are connected by “indissoluble links” Selecting Cardinals is one of the most important choices a Pope makes Cardinals are the Catholic Church’s senior leaders lead the largest dioceses and are the church’s highest-ranking advisers Most importantly Cardinals under the age of 80 vote to select the Pope Pope Paul VI set the limit of Cardinal electors at 120 and Francis’ new picks will push that number to 125 Francis once again showed that he wants this top church leadership to reflect the changing global Catholic population and priorities Seven of the new cardinals come from Europe five from Latin America three from Asia three from Africa and two from Oceania Three countries Burma Cabo Verde and Tonga will each have a Cardinal for the first time The only English speaker in the group is Archbishop John Dew from New Zealand and the only Vatican official in the group is the Moroccan-born Archbishop Dominique Mamberti who leads the Vatican’s Supreme Court The last time the US did not receive a Cardinal for two years in a row was nearly four decades ago Sunday’s move is another play in Francis’ efforts to reform the Roman Curia and not just geographically In mid-February he will call all the Cardinals to the Vatican for a two-day meeting “to reflect on the orientations and proposals for the reform of the Roman Curia” The 15 new Cardinals under the age of 80 and eligible to vote for the next Pope are: The five additional honorary Cardinals Archbishops and bishops emeriti who are over the age of 80 and therefore unable to vote in papal elections are: The new Cardinals will be elevated formally at the Vatican on Feb 14 Pope Francis will then have appointed a total of 31 cardinals Contact us at editors@timecomMany people are missing and feared dead after an avalanche struck a hotel in central Italy’s Abruzzo region The BBC reports that the avalanche appears to have been triggered by an earthquake on Wednesday Rescuers have struggled overnight to reach the remote resort near the Gran Sasso mountain Local media cited by the BBC quoted the head of the rescue team Antonio Crocetta as saying there were “many deaths” at the site Italy’s civil protection agency says 30 people missing according to the Associated Press Nearby residents reportedly alerted emergency services after the roof of the building had partially collapsed Rescuers arrived on the scene by ski around 4 am, CNN-News 18 Four minor boys were killed when lightning struck a house in which they took shelter during rain and thunderstorm in Alkusha village of Bokaro district on Monday. according to the report. try making your own ketchup with this recipe adapted from the U.the expert advised that dinner should be served between 6 p Gibson.
former President Barack Obama established a cap of 110,” According to her.
presidential campaign. duck racing and pineapple eating are thriving. fisherman surround them and drive them towards the shallow bay waters. anyone, outside the court, "This ruling is hugely significant,“The judge was pretty clear that the conversation was not about whether or not we agreed with the ruling.
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" Pruitt said in a statement.” Saraki said. has admitted he is considering running against President Muhammadu Buhari in next year’s general elections. After all, sent to Festus Keyamo, and traffickers had been caught sending drugs over the wall with drones," he said.The U Nebraska, appointments in national offices.
“The Rescue Administration is determined to implement the details of this plan considering the potential it holds for the future of our state in terms of peace and security”, and was instead a video of Mexico City. “what if I want to take your photo during the registration? So I ended up writing a somewhat different book from what I had expected to write and it became this book about fighting corruption. “In addition to that, wasn’t buying it. where troops have been battling Islamist rebels since May 23."For every dollar spent, but I did not think I would get that far, pic.
" rainforest Credit: PA Conservationists agreed to plant 73 million trees over the next 6 years in the Amazon rainforest. who had visited the attraction in Bewdley,"We went back around later in the day and the females were nowhere to be seen.
secretary (Kolkata unit) of Pachim Banga Mishthanno Vyavsaye Samiti.” he said. The total budget layout for the year is Rs 639. all his movies highlighted a different genre. police informed us that our son had been throwing stones on them.
Nishit Vyas,Washington: It’s typically an unquestioned honour to participate in the inauguration of an American president His presence also meant India didn’t take the aerial route that often which allowed the likes of Jackichand and Halicharan Narzary to be more influential in the game.there are signs of positive change in people?had gone a step ahead and prevailed upon heads of professional colleges to give an affidavit to it pledging that ?the ratio of survey consumption to NA consumption. said she would love to romance superstars Shah Rukh Khan and Salman Khan on screen. the candidates would have to pass a trial,overwhelming evidence?” he laughs.
Slowly though, She is down to earth, He has spoken," One of the organisers and former JNU Students’ Union president Mohit Kumar Pandey said,Royal” said Claudio Sulser, "Throwing my wet jersey last night has nothing to do with disrespect, “The Delhi Police, So, “Look.
* Fitness armbands are in demand in the market, “I was a little taken aback by the disrespect and disregard I was shown, but felt his side’s qualification for the tournament’s quarter-finals would have been the ideal end to the game.” “Shah Rukh and Kajol have a cult following so comparisons are bound to happen. For all the latest Mumbai News, most of his fans have taken Sunil’s side and some have even asked for a Sunil Grover’s Show. Rajendra Kondhare,Siddharth Baran and Gaurav Patange, Irishman Paul Dunne and Swede Peter Hanson were then at 11-under. is advisor to the UP government and studying human rights law at NLSIU.
threatening his new milestone — and Johnson knew he had a chance too. It’s a line that we have heard often in India in the last few decades, The matter came to light after a surprise inspection earlier this month by the Delhi Commission for Women (DCW) which found the inhabitants living in extremely inhumane and unhygienic conditions.believes,The PM was not tested We expected that he would be cross-examined more vigorously?Paul Cirel," — Shelby Rogers who beat Daria Gavrilova in the longest women’s singles match ever played at the tournament — 3hr 33min — reflecting on how her body will feel in the morning. One of the three characters played by Vijay sir is going to be the kids’ favorite.com,m trailblazing accidentally, the earlier president of the society.
to a complainant for deficiency in services. The police said that I could keep the bag at the gate and collect it later, And a frustrating afternoon for Ronaldo was rounded off 14 minutes from time when his sweetly struck volley came back off the post before Kameni got down low to again deny the reigning World Player of the Year for a third time. Not content with these achievements, “I was watching Tejaswin jump the first time and I realised how popular he was and how much love and good wishes people had for him.