Russian space experiments lead to a new 3D bioprinting technique

first_img More information: Vladislav A Parfenov et al, Scaffold-free, label-free and nozzle-free biofabrication technology using magnetic levitational assembly, Biofabrication (2018). DOI: 10.1088/1758-5090/aac900 Schematic image of an experimental setup with a “magnetic well” trap for holding bio-objects. Credit: Vladislav A Parfenov et al // Biofabrication, 2018 The conventional methods of magnetic 3-D bioprinting had a number of limitations associated with the gravity. To reduce the influence of the gravitational forces, one can increase the power of magnets that control the magnetic field. However, this will complicate the bioprinter considerably. The second way is to reduce the gravity. A group of scientists from 3-D Bioprinting Solutions used this approach. The new method is called formative three-dimensional biofactory, and it creates three-dimensional biological structures not in layers but immediately from all the sides. The researchers applied the experimental data and the results of the mathematical modeling obtained by the JIHT RAS scientists to control the shape of such structures.”The results of the Coulomb crystal experiment on the study of the formation of the spatially ordered structures led to the development of a new method for the formative 3-D biofactory of the tissue-like structures based on the programmable self-assembly of the living tissues and organs under the conditions of gravity and microgravity by means of an inhomogeneous magnetic field,” said the author.Bioprinters based on the new technology application will be able to create various biological constucts that can be used, for example, to estimate the adverse effects of space radiation on the health of astronauts on long-term space missions. In addition, this technology will be able to restore the function of the damaged tissues and organs in the future. In their experimental study, the JIHT researchers described how small charged particles behave in the magnetic field of a special shape under the microgravity conditions, including zero gravity. In addition, the scientists developed a mathematical model of this process based on the methods of molecular dynamics. These results explain how to obtain homogeneous and extended three-dimensional structures consisting of the thousands of the particles. Provided by AKSON Russian Science Communication Association The process of 3D self-assembly in the “magnetic well”. Credit: Vladislav A Parfenov et al // Biofabrication, 2018 Explore further Journal information: Biofabrication There are many methods of 3-D bioprinting. Most of them use a certain layer-by-layer framework of the biological tissues. The resulting bulk material is then sent to the incubator where the cultivation continues. There are ways in which biological objects are developed without the use of a multi-layer approach, for example, magnetic bioprinting, in which the cell material is directed to the desired location by means of magnetic fields. In this case, the cells should be labeled in some way with magnetic nanoparticles.The researchers from the 3-D Bioprinting Solutions company in collaboration with the other Russian and foreign scientists developed the new method, which allows researchers to create 3-D biological objects without the use of layer-by-layer approach and magnetic labels. This new method was developed with the contribution from the Joint Institute for High Temperatures of the Russian Academy of Sciences (JIHT RAS).”During the period from 2010 to 2017, a series of experimental studies were carried out aboard the Russian Orbital Segment of the International Space Station with the Coulomb Crystal experimental device. The main element of the device is an electromagnet that creates a special inhomogeneous magnetic field in which the structures of the diamagnetic particles (they are magnetized against the direction of the magnetic field) can be formed in the microgravity conditions,” says co-author Mikhail Vasiliev, head of laboratory of dusty plasma diagnostics in JIHT RAS. Citation: Russian space experiments lead to a new 3-D bioprinting technique (2018, June 26) retrieved 18 July 2019 from https://phys.org/news/2018-06-russian-space-d-bioprinting-technique.html Thanks to magnetic levitation research in conditions of microgravity, scientists have developed a new technology for 3-D printing of biological tissues. In the future, this technology will help to create radiation-sensitive biological constructs and repair damaged tissues and human organs. The results are published in Biofabrication. Cell cultures go for the gold This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

EU set to fine Google billions over Android sources

first_imgGoogle also gave “financial incentives” to manufacturers and mobile network operators if they pre-installed Google Search on their devices, the commission said.Vestager’s other scalps include Amazon and Apple.The EU’s biggest ever punishment targeted Apple in 2016 when it ordered the iconic maker of iPhones and iPads to pay Ireland 13 billion euros ($16 billion) in back taxes that it had avoided by a tax deal with Dublin.The EU has also taken on Facebook over privacy issues after it admitted that millions of users may have had their data hijacked by British consultancy firm Cambridge Analytica, which was working for Trump’s 2016 election campaign.The Google decision comes just one week before European Commission chief Jean-Claude Juncker is due to travel to the United States for crucial talks with Trump on the tariffs dispute and other issues.Transatlantic tensions are also high after Trump berated NATO allies over defence spending at a summit last week, over his summit with Russian leader Vladimir Putin, and over the US president’s pull-out from the Iran nuclear agreement and Paris climate deal. Competition Commissioner Margrethe Vestager is expected to say on Wednesday that Google abused its dominant position in the market by making tie-ups with phone makers like South Korea’s Samsung and China’s Huawei.The long-awaited decision comes as fears of a transatlantic trade war mount due to President Donald Trump’s shock decision to impose tariffs on European steel and aluminium exports.Two European sources told AFP the fine would be “several billion euros” without giving further details. EU rules say Google could be fined up to 10 percent of parent company Alphabet’s annual revenue, which hit $110.9 billion in 2017.”The fine is based on the length of the infraction, but also on whether anti-trust authorities believe there was an intention to commit the offence, and whether they excluded competitors or not,” said another source close to the matter.The European Commission, the 28-nation EU’s executive arm, refused to comment.Denmark’s Vestager has targeted a series of Silicon Valley giants in her four years as the 28-nation European Union’s anti-trust chief, winning praise in Europe but angering Washington.The case against Android is the most significant of three complaints by the EU against the search titan, which has already been hit with a record-breaking 2.4-billion-euro fine in a Google shopping case.Brussels has repeatedly targeted Google over the past decade amid concerns about the Silicon Valley giant’s dominance of Internet search across Europe, where it commands about 90 percent of the market. © 2018 AFP ‘Financial incentives’In the Android file, the European Commission has accused Google of requiring mobile manufacturers such as Samsung and Huawei to pre-install its search engine and Google Chrome browser on phones, and to set Google Search as the default, as a condition of licensing some Google apps.Google Search and Chrome are as a result pre-installed on the “significant majority” of devices sold in the EU, the commission says.The complaint formally lodged in April also accuses Google of preventing manufacturers from selling smartphones that run on rival operating systems based on the Android open source code. Google is facing a massive fine from the EU this week for abusing its dominant market position Google faces EU anti-trust fines over Android: sources Explore further This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Citation: EU set to fine Google billions over Android: sources (2018, July 17) retrieved 18 July 2019 from https://phys.org/news/2018-07-eu-fine-google-billions-android.html The EU is set to fine US internet giant Google several billion euros this week for freezing out rivals of its Android mobile phone system, sources said, in a ruling that risks fresh tensions with Washington. EU competition commissioner Margrethe Vestager is expected to say Google abused its dominant market position and to impose a multi- billion dollar fine on the internet giantlast_img read more

Pinterest reports smaller 1Q loss but results drag stock

first_img © 2019 The Associated Press. All rights reserved. In this Thursday, April 18, 2019, file photo, Pinterest co-founder and chief product officer Evan Sharp, left, and fellow co-founder & CEO Ben Silbermann, right, watch as company communications manager Enid Hwang rings a ceremonial bell when their IPO begins trading on the New York Stock Exchange floor. Pinterest, fresh off its initial public offering, is reporting a smaller loss in the first quarter, boosted by higher revenue, but its outlook was below expectations and shares slumped in after-hours trading. (AP Photo/Richard Drew, File) Explore further Pinterest, fresh off its initial public offering, posted a loss for the first three months of the year that was larger than analysts were expecting, though revenue was slightly stronger. Its revenue forecast, though, was slightly below expectations and its shares slumped in after-hours trading. LinkedIn reports 3Q loss but sales climbcenter_img The company, which runs a digital pinboard and shopping tool, said Thursday that its net loss was $41.4 million, or 33 cents per share, in the January-March period. Its revenue grew 54% to $202 million from $131 million. The quarter’s adjusted loss was 32 cents per share.Analysts had expected a loss of 11 cents per share on revenue of $200.7 million, according to FactSet.People use Pinterest to search for and collect, or “pin,” ideas for weddings, home decor, recipes, fashion and other categories. The service had 291 million monthly active users in the first quarter, up 22% from 239 million a year earlier.Pinterest said it expects revenue in a range of $1.055 billion to $1.08 billion for the full year, the midpoint of which is slightly below the $1.07 billion that analysts had been expecting, even though the first quarter’s sales surpassed estimates.The San Francisco-based company’s shares fell $4.86, or 16 percent, to $26 in after-hours trading. The stock had closed the regular-trading day up $2.23, or 7.8 percent, at $30.86. The company went public at $19 per share in April. Citation: Pinterest reports smaller 1Q loss but results drag stock (2019, May 16) retrieved 17 July 2019 from https://phys.org/news/2019-05-pinterest-smaller-1q-loss-guidance.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

Watch Car performs stunt at Delhis Vijay Chowk

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